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Hengrui Pharma: HRS-4729 injection was approved for clinical trial. Hengrui Pharma announced that the company and its subsidiary Fujian Sheng Di Pharmaceutical Co., Ltd. received the Notice of Approval for Clinical Trial of HRS-4729 injection approved and issued by National Medical Products Administration. The drug is a polypeptide drug independently developed, and it is a GLP-1R/GIPR/GCGR triple agonist, which is suitable for obese or overweight patients. Up to now, HRS-4729 injection has invested about 19.56 million yuan in research and development.Oppenheimer: Raise the target price of opening customers from $980 to $1,075, and reiterate the rating of "outperforming the market".Australia's S&P/ASX200 index opened down 12.60 points, or 0.15%, at 8380.4 points on Wednesday, December 11th.

The commander of Syrian democratic forces said that under the mediation of the US, Syrian rebels and Syrian democratic forces reached a ceasefire agreement in the northern city of Mambiji.Eight people were killed when the Israeli army attacked a house in the central part of Gaza, and eight people were killed and many others were injured when the Israeli army bombed a house in Nuseilet refugee camp in the central part of Gaza on the evening of 10th local time.Zhejiang Alibaba Cloud has invested in Sealos, and Tianyancha App shows that recently, Sealos affiliated company Zhuhai Huanjie Cloud Computing Co., Ltd. has undergone industrial and commercial changes, adding Zhejiang Alibaba Cloud Computing Co., Ltd. as a shareholder, and the registered capital has increased from about 2.679 million RMB to about 3.349 million RMB. Zhuhai Huanjie Cloud Computing Co., Ltd. was established in March 2022, and its legal representative is Fang Haitao. Its business scope includes computer software and hardware and auxiliary equipment wholesale, computer software and hardware and auxiliary equipment retail, cloud computing equipment technical services, etc. Now it is jointly held by Fang Haitao, Hangzhou Fanjie Enterprise Management Partnership (Limited Partnership) and the above-mentioned new shareholders. Official website shows that the company focuses on developing and providing cloud native ecological products and services.

Xia Yiping, CEO of Extreme Vietnam: The company is experiencing difficulties at present, and the company needs to adjust immediately. On December 11th, it was learned from the inside of Extreme Vietnam Automobile that Xia Yiping, CEO of Extreme Vietnam, communicated with all employees through video conference, frankly indicating that the company is experiencing difficulties at present, and the company needs to adjust immediately and enter the 2.0 stage of entrepreneurship. The management will go all out to tide over the difficulties with all employees. Xia Yiping said that in the new entrepreneurial period, the following four things must be done well: 1. Adhere to the long-term investment in core technologies to maintain the leading edge; 2. Strengthen sales and service capacity building to cope with fierce market competition; 3. Merge departments and posts with duplicate functions and change inefficient internal workflow; 4. Reduce projects that cannot improve financial performance in the short term. (Blue Whale Finance)The National Southeast Regional Emergency Rescue Center is about to be delivered. It was learned from the recent press conference held in Chaozhou, Guangdong that the National Southeast Regional Emergency Rescue Center is about to be delivered. The National Southeast Regional Emergency Rescue Center is located in Chao 'an District, Chaozhou City, Guangdong Province. It is one of the six national regional emergency rescue centers in China, focusing on the emergency rescue of typhoons and their secondary and derivative disasters. It has basic functions such as emergency command, comprehensive rescue, training drills, equipment storage and transportation, etc., to ensure that it can reach the disaster area in the shortest time to complete the difficult rescue task. (CCTV News)Zhongzhou Special Materials: Shareholders have transferred and reduced their shares by more than 1%. Zhongzhou Special Materials announced that shareholders holding more than 5% have transferred their shares internally and reduced their shares by more than 1%. After the shareholder completed the internal transfer among the concerted parties, its shareholding ratio changed accordingly. At the same time, the shareholder reduced his shares through the secondary market, and the reduction ratio exceeded 1%. This share change is mainly for the adjustment of shareholding within the company's shareholders, and will not have a significant impact on the company's governance structure and daily operations.